Introduction: The majority of patients with Marfan syndrome undergo Bentall procedure. Several periprocedural complications may arise; cardiac complications play the most dominant role. Case presentation: A patient with Marfan syndrome developed symptoms two years after the Bentall procedure. Coronary CT angiography revealed bilateral coronary ostial stenosis. Percutaneous coronary intervention was performed, and two drug-eluting stents were implanted. Conclusions: Coronary CT angiography is a valuable tool for the examination of symptomatic patients following surgical aortic root replacement.