Angiotensin-converting Enzyme inhibitors-induced Angioedema

Author(s):

Anca Chiriac¹,²,³, Piotr Brzezinski⁴,⁵,⁶,⁷, Mircea Betiu8, Liliana Foia9

Affiliation:

¹ Nicolina Medical Center, Department of Dermatology, Iași, Romania
² Apollonia University, Iași, Romania
³ “P. Poni” Research Institute, Romanian Academy, Iasi
⁴ Department of Dermatology, 6th Military Support Unit, Ustka, Poland
⁵ Department of Dermatology, Provincial Specialist Hospital in Slupsk, Ustka, Poland
⁶ Institute of Biology and Environmental Protection, Pomeranian Academy, Slupsk, Poland
⁷ Faculty of Mathematics and Natural Sciences, Institute of Biology and Environmental Protection, Pomeranian Academy, Slupsk, Poland
8 Department of Dermatovenereology, “Nicolae Testemitanu” State University of Medicine and Pharmacy, Chișinău, Republic of Moldova
9 “Grigore T Popa” University of Medicine and Pharmacy, Iași, Romania

DOI: 10.2478/jce-2018-0004

ABSTRACT

Angiotensin-converting enzyme inhibitors (ACEI) are widely used drugs nowadays in treating patients diagnosed with cardiovascular disorders. We present two consecutive cases of acquired angioedema caused by the administration of enalapril and lisinopril in patients with indication for ACE-inhibitors therapy. Rigorous follow-up of side effects of ACEI is required, due to these possible life-threatening adverse reactions.